-
Medical
Outcomes 01: Patient Health Indicators
Near Enrollment by Client Need and Vulnerability Categories
Final.
This Knowledge Item shows the
levels of three medical indicators of the stage of HIV disease–viral loads, CD4 counts, and CD4 Classification categories–for
patients at the first time they were assessed by the medical programs.
-
Medical
Outcomes 02: Empirical Models of Viral Load and Patient Need and
Vulnerability Categories Near Enrollment
Final.
This Knowledge Item shows
that viral loads at the earliest time they are measured
in medical programs are systematically related to selected patient characteristics.
-
Medical
Outcomes 03: Empirical Models of CD4 Counts and Patient Need and
Vulnerability Categories Near Enrollment
Final.
This Knowledge Item shows that CD4 counts at the earliest time they are measured
in medical programs are systematically related to selected patient characteristics.
-
Medical
Outcomes 04: Empirical Models of CD4 Classifications and Patient Need and Vulnerability Categories Near
Enrollment
Final.
This Knowledge Item shows that CD4 Classification status near the time of enrollment is systematically related to selected patient characteristics.
-
Medical
Outcomes 05: Empirical Models of
Karnofsky Severity Rating and Patient Need and
Vulnerability Categories Near Enrollment
Final.
This Knowledge Item shows that Karnofsky Severity
Ratings made at the earliest time measured
in medical programs are systematically related to selected patient characteristics.
-
Medical Outcomes 06:
Gender Differences in Measures of Disease Severity Near Enrollment
Final.
This Knowledge Item shows that gender is related to medical
indicators of HIV disease obtained near the time of program
enrollment.
-
Medical Outcomes 07:
Ethnic-Racial Group Differences in Measures of Disease Severity Near
Enrollment
Final.
This Knowledge Item shows that racial-ethnic group is related to
the stage of disease at which HIV/AIDS patients enter medical
treatment.
-
Medical
Outcomes 08:
Empirical Models of AIDS-defining Condition and Patient Need and Vulnerability
Categories
Final.
This Knowledge Item shows how
the development of an
AIDS-defining condition during the course of treatment is systematically related to selected patient characteristics.
-
Medical
Outcomes 09: Health Indicators and Patient Self-Rated
Quality of Life
Final.
This Knowledge Item shows the
levels of four medical indicators of the stage of HIV disease–viral loads, CD4 counts, and CD4 Classification categories–for
patients at the first time they were assessed by the medical programs
and self-rated quality of life throughout the treatment episode.
-
Medical
Outcomes 11: Maximum Degree of Improved Quality of Life as a Function
of the Type of Medical Project Providing Treatment
Final.
This knowledge item shows the maximum
improvement in quality of life functioning that is obtained by Managed
Care and Comprehensive Healthcare Projects. Initial levels of quality of
life and initial levels of physical functioning (as measured by CD4
count) are controlled. The Comprehensive Healthcare model (with
integrated wrap-around services) achieves better patient-reported
quality of life outcomes.
-
Medical
Outcomes 12: Length of Time a Participant is Maintained at the
Same or an Improved Quality of Life as a Function of the Type of
Medical Project Providing Treatment
Final.
This knowledge item shows the probability of maintaining an
individual at or above the baseline Total Quality of Life Score in the
Managed Care and Comprehensive Healthcare Projects. Initial levels of quality of
life and initial levels of physical functioning (as measured by CD4
count) are controlled. The Comprehensive Healthcare model (with
integrated wrap-around services) achieves better patient-reported
quality of life outcomes.
-
Medical
Outcomes 13: Length of Time a Participant is Maintained at the
Same or an Improved Quality of Life as a Function of the Type of
Medical Project Providing Treatment (Further Control for Initial
Functioning Levels)
Final.
This knowledge item shows the probability of maintaining an
individual at or above the baseline Total Quality of Life Score in the
Managed Care and Comprehensive Healthcare Projects. Initial levels of quality of
life and initial levels of physical functioning (as measured by CD4
count, viral load, Karnofsky Severity Ratings) are controlled. The
Comprehensive Healthcare model (with integrated wrap-around services)
achieves better patient-reported quality of life outcomes.
-
Medical Outcomes 14: Hierarchical Linear Models
Showing Change in CD4 Counts
Final.
This Knowledge Item presents hierarchical linear
models of changes in CD4 counts during the treatment episode.
-
Medical Outcomes 15: More Complex Hierarchical Linear
Models Showing Differential Change in CD4 Counts for Groups Formed by Needs and
Vulnerabilities
Final.
This Knowledge Item presents hierarchical linear
models of changes in CD4 counts during the treatment episode. The degree
of change is related to a series of service needs and vulnerabilities.
-
Medical Outcomes 16: Length of Time Maintained at the
Same or an Improved CD4 Count as a Function of Treatment in
Different Types of Programs
Final.
This Knowledge Item
contrasts the relative ability of two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to maintain patients at
100% or better of
their baseline CD4 count.
-
Medical Outcomes 17: Maximum Degree of Improved
CD4 Counts as a Function of Treatment in
Different Types of Programs
Final.
This Knowledge Item shows how the maximum change in
CD4 count over the course of the treatment episode was estimated and is
related to a number of factors, including most importantly the relative ability of
two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to improve the overall
physical functioning as measured by CD4 counts.
-
Medical Outcomes 18: Hierarchical Linear Models
Showing Change in Karnofsky Severity Ratings
Final.
This Knowledge Item presents hierarchical linear
models of changes in Karnofsky Severity Ratings.
-
Medical Outcomes 19: More Complex Hierarchical Linear
Models Showing Differential Change in Karnofsky Severity Ratings for Groups Formed by Needs and
Vulnerabilities
Final.
This Knowledge Item presents hierarchical linear
models of changes in Karnofsky Severity Ratings during the treatment episode.
The degree of change is related to a series of service needs and
vulnerabilities.
-
Medical Outcomes 20:
Length of Time Maintained at the
Same or an Improved Karnofsky Severity Rating as a Function of
Treatment in Different Types of Programs
Final.
This Knowledge Item
contrasts the relative ability of two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to maintain patients at
100% or better of their baseline Karnofsky Severity Rating.
-
Medical Outcomes 21: Maximum Degree of Improved
Karnofsky Severity Rating as a Function of Treatment in
Different Types of Programs
Final.
This Knowledge Item shows how the maximum change in
CD4 count over the course of the treatment episode was estimated and is
related to a number of factors, including most importantly the relative ability of
two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to improve the overall
physical functioning as measured by Karnofsky Severity Ratings.
-
Medical Outcomes 22: Hierarchical Linear Models
Showing Change in Viral Loads
Final.
This Knowledge Item presents hierarchical linear
models of changes in viral load test results during the treatment episode.
The degree of change is related to a series of service needs and
vulnerabilities.
-
Medical Outcomes 23: More Complex Hierarchical Linear
Models Showing Differential Change in Viral Loads for Groups Formed by Needs and
Vulnerabilities
Final.
This Knowledge Item presents hierarchical linear
models of changes in viral loads during the treatment episode. The
degree of change is related to a series of service needs and
vulnerabilities.
-
Medical Outcomes 24:
Length of Time Maintained at the
Same or an Improved Viral Load as a Function of Treatment in
Different Types of Programs
Final.
This Knowledge Item
contrasts the relative ability of two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to maintain patients at
100% or better of
their baseline viral load.
-
Medical Outcomes
25: Maximum Degree of Improved Viral Load as a Function of
Treatment in Different Types of Programs
Final.
This Knowledge Item shows how the maximum change in
CD4 count over the course of the treatment episode was estimated and is
related to a number of factors, including most importantly the relative ability of
two kinds of services–managed
medical care; comprehensive medical care including
"wrap-around" social services–to improve the overall
physical functioning as measured by decreased viral loads.
-
Medical Outcomes 26:
More Complex Hierarchical Linear
Models Showing Differential Change in CD4 Counts for Groups Formed by
Demographic Categories and Drug Abuse Status
Final.
This Knowledge Item shows models of the relationship
of changes in CD4 counts, derived from Hierarchical Linear Models, to
demographic factors and drug abuse status.
-
Medical Outcomes 27:
More Complex Hierarchical Linear
Models Showing Differential Change in Karnofsky Severity Ratings for Groups Formed by
Demographic Categories and Drug Abuse Status
Final.
This Knowledge Item shows models of the relationship
of changes in Karnofsky Severity Ratings, derived from Hierarchical
Linear Models, to demographic factors and drug abuse status.
-
Medical Outcomes 28:
More Complex Hierarchical Linear
Models Showing Differential Change for Groups Formed by Demographic
Categories and Drug Abuse Status
Final.
This Knowledge Item shows models of the relationship
of changes in viral loads, derived from Hierarchical Linear Models, to
demographic factors and drug abuse status.
-
Medical Outcomes 29:
Relationship of Change in Quality of Life, CD4 Counts, Karnofsky
Ratings, and Viral Loads
Final.
This Knowledge Item examines the
level of change shown for patients in terms of four major indicators
of self-rated quality of life, medical-provider-rated disease severity
(Karnofsky Severity Ratings), CD4 count, and viral load.
-
Medical Outcomes
30: Degree of Change in CD4 Counts and Total Service Needs and
Vulnerabilities
Final.
This Knowledge Item shows the
relationship of the degree of change in CD4 counts over time and the
total number of service needs and vulnerabilities (of 15).
-
Medical Outcomes
31: Degree of Change in Karnofsky
Severity Ratings and Total Service Needs and Vulnerabilities
Final.
This Knowledge Item shows the
relationship of the degree of change in Karnofsky Severity Ratings and the
total number of service needs and vulnerabilities (of 15).
-
Medical Outcomes
32: Degree of Change in Viral
Loads and Total Service Needs and Vulnerabilities
Final.
This Knowledge Item shows the
relationship of the degree of change in viral loads over time and the
total number of service needs and vulnerabilities (of 15).
-
Medical Outcomes
33: Relationship of Changes in CD4 Counts to Treatment History
Including the Use of HAART Therapies
Final.
This Knowledge Item Shows models of the
relationship of changes in CD4 counts, derived from Hierarchical
Linear Models, to experience with HAART therapies, and other
service components.
-
Medical Outcomes
34: Relationship of Changes in Karnofsky Severity Ratings to
Treatment History Including the Use of HAART Therapies
Final.
This Knowledge Item shows models of the relationship of
changes in Karnofsky Severity Ratings, derived from Hierarchical
Linear Models, to experience with HAART therapies, and other
service components.
-
Medical Outcomes
35: Relationship of Changes in Viral Loads to Treatment History
Including the Use of HAART Therapies
Final.
This Knowledge Item shows models of the
relationship of changes in viral loads, derived from Hierarchical
Linear Models, to experience with HAART therapies, and other
service components.
-
Medical Outcomes
36: Relationship of Changes in Quality of Life to the Use of HAART
Therapies
Final.
This Knowledge Item shows, through
direct and post hoc analyses of the hierarchical linear model on patient-rated
quality of life results, that quality of life changed to about the
same degree for patients whether or not they received HAART.
-
Medical Outcomes
37: Number of Triple Combination Therapies Received and Changes in
CD4 Count, Viral Load, Karnofsky Severity Index, and Quality of Life
Final.
This Knowledge Item examines the
relationship between the number of triple combination therapies
administered to a patient and the degree of change in objective (CD4
count, viral load), subjective clinician rating (Karnofsky), and
patient perception (quality of life) of medical functioning.
-
Medical Outcomes
39: Changes in Self Reported Symptoms and Changes in Medical
Indicators
Final.
This Knowledge Item examines the
relationship of the degree of change in self-reported symptom
severity, and the degree of change in self-rated quality of life,
medical-provider-rated disease severity (Karnofsky Severity Ratings),
CD4 count, and viral load.
-
Medical
Outcomes 40:
Participant Satisfaction and Change in CD4 Counts, Viral Loads,
Quality of Life, and Karnofsky Severity Ratings
Final.
This Knowledge Item shows that
patients who have relatively the most improvement in their quality of
life and whose clinicians rate their progress as most improving (or
least deteriorating) rate the quality of their programs most highly.
